A case of CRS & HIPEC: A 57-year-old female was presented to Jaypee Hospital, Noida with

 **STAGE – III C* *Ovarian Cancer *. Given her advance stage, doctors planned her treatment accordingly. Dr. Atul Sharma, Senior Consultant – Department of Medical Oncology started treatment with chemotherapy. After primary chemotherapy, Dr. Ashish Goel, Director, and Dr. Vikash Nayak, Consultant – Department of Surgical Oncology did a *CYTOREDUCTIVE SURGERY* to remove all the affected parts, followed by a *HIPEC* therapy (in the operation theatre).  This offers the best result in such advanced cases of ovarian cancer. After surgery, she completed subsequent chemotherapy. Now the patient is doing well. The happy patient and her daughter share their experience in this video.

Cytoreductive surgery the most common treatment for treatment of ovarian cancer. the surgery involves removal of tumor and its spread in nearby tissues.

Dr Ashish Goel is the best cancer surgeon in Noida. With 25+ years of experience, he is the most trusted oncologist

CRS (Cytoreductive Surgery) and HIPEC (Hyperthermic Intraperitoneal Chemotherapy) are two components of a combined treatment approach used for certain types of advanced abdominal cancers, such as advanced ovarian cancer or pseudomyxoma peritonei.

Cytoreductive surgery (CRS) involves the surgical removal of visible tumors within the abdominal cavity. The goal is to remove as much tumor tissue as possible, reducing the tumor burden. This procedure aims to improve the effectiveness of subsequent treatments and potentially increase the patient’s overall survival rate.

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a specialized form of chemotherapy delivered directly into the abdominal cavity during surgery. After CRS, a heated chemotherapy solution is circulated throughout the abdominal cavity to target any remaining cancer cells that may not be visible or accessible to surgical removal. The high temperature of the chemotherapy solution enhances its effectiveness in destroying cancer cells.

The combination of CRS and HIPEC aims to achieve two goals:

1. Cytoreduction: By removing visible tumors during CRS, the surgeon attempts to eliminate as much cancerous tissue as possible. The goal is to reduce the tumor burden and enhance the effectiveness of subsequent treatments.
2. Intraperitoneal Chemotherapy: HIPEC allows for the delivery of chemotherapy directly into the abdominal cavity, where it can reach any remaining cancer cells. The heat applied during HIPEC improves the penetration and effectiveness of the chemotherapy drugs.

This combined approach is typically performed in specialized centers by a multidisciplinary team of surgical oncologists, medical oncologists, and other healthcare professionals experienced in treating advanced abdominal cancers. The decision to use CRS and HIPEC depends on various factors, including the type and stage of cancer, the patient’s overall health, and their eligibility for such an extensive procedure.

It’s important to note that CRS and HIPEC are complex treatments and require careful patient selection and evaluation. The decision to pursue this treatment approach is made on an individual basis after a thorough assessment by the healthcare team.